Td Vax Adverse Reactions

Frequencies of adverse reactions are defined as follows: Very common (≥ 1/10); common (≥ 1/100 to <1/10); uncommon (≥ 1/1,000 to <1/100); rare (≥ 1/10,000 to <1/1,000); very rare (<1/10,000); not known (cannot be estimated from the available data).
Adverse reactions observed in clinical trials: General disorders and administration site conditions: Very common: Fever, malaise, injection site reaction and/or injection site pain.
Adverse reactions from post-marketing spontaneous monitoring (frequency not known): Blood and lymphatic system disorders: Thrombocytopenia; enlargement, painfulness of local lymph nodes.
Immune system disorders: Hypersensitivity (including generalized rash or local rash, itching, swelling of face and laryngospasm) the occurrence of anaphylactic shock inclusive.
Nervous system disorders: Headache; dizziness; central and peripheral nervous system disorders; afebrile convulsions; fainting, loss of consciousness, hypotonia; paresis of the limb in which vaccination was administered, which may be a sign of palsy or brachial plexus neuritis; Guillain-Barre syndrome.
Gastrointestinal disorders: Digestive system disorders (nausea, vomiting, abdominal pain).
Musculoskeletal and connective tissue disorders: Injected limb mobility decreased, pain in extremity, swelling and warmth of the joint of the limb, in which vaccination was administered; muscle pain.
Renal and urinary disorders: Renal failure.
General disorders and administration site conditions: General adverse reactions: Fever, chills, hyperhidrosis, malaise, these symptoms usually subside within 24-48 hours.
Adverse reactions at the administration site: Redness, pain, swelling and itching. Itchy lymphatic infiltration can also appear. These kinds of reactions occur most commonly in repeatedly vaccinated patients. Subcutaneous nodules - granulomas may occur, which sometimes develop into aseptic abscesses (1:100 000). Granulomas which fail to subside within 6 weeks may be the result of developing hypersensitivity to aluminium.